Men’s blood has higher ranges than women’s of a crucial enzyme utilized by the new coronavirus to infect cells, the outcomes of a big European study showed Monday — a finding which may assist in explaining why men are weaker to infection with COVID-19.
Angiotensin-converting enzyme 2 (ACE2) is found in the heart, kidneys and other organs. In COVID-19, the respiratory illness attributable to COVID-19, it’s thought to play a role in how the infection progresses into the lungs.
The research, revealed in the European Heart Journal, discovered that widely-prescribed medicine called ACE inhibitors or angiotensin receptor blockers (ARBs) didn’t result in increased ACE2 concentrations and will therefore not increase the COVID-19 danger for individuals taking them.
ACE inhibitors and ARBs are broadly prescribed to sufferers with congestive heart failure, diabetes or kidney illness—the medicine account for billions of dollars in prescription sales globally.
The COVID-19 pandemic has infected over four million individuals worldwide and killed 277,000. Death and infection tolls point to men being more likely than women to get infected by the disease and to suffer complications if they do.
Analysing thousands of women and men, Voors’ crew measured ACE2 concentrations in blood samples taken from over 3,500 heart failure sufferers from 11 European nations.